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Vitamin D3 is often referred to as the sunshine vitamin in reference to the skin’s ability to produce it from sunlight and ultraviolet light. As little as 15 minutes spent in the sun can generate up to 5000IU of vitamin D.

 

WHY WE ENCAPSULATE IN OLIVE OIL

Vitamin D3 is a fat-soluble compound, meaning it must be consumed with a fat source to absorb it efficiently. Taking vitamin D3 supplements with fatty foods can help achieve this, but research shows that taking vitamin D3 with an oil as a carrier vehicle provides superior absorption. Elevated Healing has selected olive oil to ensure maximum vitamin D3 uptake. Other oils, such as corn, safflower, or soybean oil, are poor carriers for several reasons. For example, corn and soybean oil are only fatty structures, whereas olive oil is a true fat. Unlike other oils, olive oil has a synergy with vitamin D3 that reduces inflammation and oxidative stress. Additionally, allergies to olive oil are rare, unlike soy.

 

VITAMIN D FOR THE IMMUNE SYSTEM

Vitamin D3 supports our immune function in several ways. It’s an immunoregulator that activates the body’s natural defences against pathogens and aid in eliminating toxins. It defends against invading pathogens by enhancing T-cell function. Vitamin D3 also stimulates the macrophages that surround and destroy pathogens. Insufficient vitamin D3 impairs immune function and increases the likelihood of developing illnesses or infectious diseases. Individuals with vitamin D3 deficiencies are particularly at risk of developing respiratory illnesses, as insufficient vitamin D3 in particular impairs lung function.

 

CANCER PREVENTION

Vitamin D has shown anti-cancer effects in vitro and in vivo for almost all cancer types. Like vitamin C, it targets the mitochondria by improving metabolism and regulating mitochondrial respiration. Vitamin D can also target cancer stem cells  and metastases , and inhibit glycolysis and glutaminolysis pathways. It has been observed that daily vitamin D supplementation can reduce total cancer mortality, but this has not been observed for infrequent large bolus doses. Cancer patients are often deficient in vitamin D and they can benefit from effective therapy with minimal risk.

 

VITAMIN D FOR STRONG TEETH AND BONES

One of Vitamin D3’s most important function include the formation and maintenance of strong bones, cartilage, and teeth. Adequate absorption of calcium and phosphorous are essential for healthy teeth and bones. Vitamin D3 enhances the absorption of these compounds in the small intestines. It also regulates the rate of bone turnover and calcium release. Additionally, research shows vitamin D3 decreases the likelihood of fractures from falls in the elderly population.

 

OTHER BENEFITS OF VITAMIN D3

Vitamin D3 provides several other health benefits. For example, vitamin D3 improves mood, increases upper and lower body strength, supports weight loss efforts, and may enhance longevity.

 

VITAMIN D3 DEFICIENCY SYMPTOMS

Adults deficient in Vitamin D3 may suffer from a condition known as osteomalacia. Vitamin D 3deficiencies also increase the risk of developing osteoporosis, which weakens bones and increases the probability of bone fractures. Vitamin D3 deficiencies also increase the risk of severe acute respiratory infections.  This fact was painfully exhibited during the recent C19 outbreak where 88% of people that had severe illness were Vit D3 deficient

 

References:

Chakraborti, C. K. (2011). “Vitamin D as a promising anticancer agent.” Indian J Pharmacol. 43(2): 113-120. https://doi.org/10.4103/0253-7613.77335.

‘Seraphin, G., Rieger, S., Hewison, M., Capobianco, E., and Lisse, T. S. (2023). “The impact of vitamin D on cancer: A mini review.” J Steroid Biochem Mol Biol. 231: 106308. https://doi.org/10.1016/j.jsbmb.2023.106308.

Matta Reddy, A., Iqbal, M., Chopra, H., Urmi, S., Junapudi, S., Bibi, S., Kumar Gupta, S., Nirmala Pangi, V., Singh, I., and Abdel-Daim, M. M. (2022). “Pivotal role of vitamin D in mitochondrial health, cardiac function, and human reproduction.” Excli j. 21: 967-990. https://doi.org/10.17179/excli2022-4935.

Quigley, M., Rieger, S., Capobianco, E., Wang, Z., Zhao, H., Hewison, M., and Lisse, T. S. (2022). “Vitamin D Modulation of Mitochondrial Oxidative Metabolism and mTOR Enforces Stress Adaptations and Anticancer Responses.” JBMR Plus. 6(1): e10572. https://doi.org/10.1002/jbm4.10572.

Marigoudar, J. B., Sarkar, D., Yuguda, Y. M., Abutayeh, R. F., Kaur, A., Pati, A., Mitra, D., Ghosh, A., Banerjee, D., Borah, S., Barman, K., Das, B., Khairnar, S. J., Šeherčehajić, E., and Kumar, S. (2022). “Role of vitamin D in targeting cancer and cancer stem cell populations and its therapeutic implications.” Med Oncol. 40(1): 2. https://doi.org/10.1007/s12032-022-01855-0.

Sheeley, M. P., Andolino, C., Kiesel, V. A., and Teegarden, D. (2022). “Vitamin D regulation of energy metabolism in cancer.” Br J Pharmacol. 179(12): 2890-2905. https://doi.org/10.1111/bph.15424.

Hohaus, S., Tisi, M. C., Bellesi, S., Maiolo, E., Alma, E., Tartaglia, G., Corrente, F., Cuccaro, A., D’Alo, F., Basile, U., Larocca, L. M., and De Stefano, V. (2018). “Vitamin D deficiency and supplementation in patients with aggressive B-cell lymphomas treated with immunochemotherapy.” Cancer Med. 7(1): 270-281. https://doi.org/10.1002/cam4.1166.

National Center for Biotechnology Information. PubChem Compound Summary for CID 5280795, Cholecalciferol. https://pubchem.ncbi.nlm.nih.gov/compound/Cholecalciferol. Accessed Oct. 31, 2024.

Anthony W Norman, From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health1, The American Journal of Clinical Nutrition, Volume 88, Issue 2, 2008, Pages 491S-499S, ISSN 0002-9165,(https://www.sciencedirect.com/science/article/pii/S0002916523241039

Bendik I, Friedel A, Roos FF, Weber P, Eggersdorfer M. Vitamin D: a critical and essential micronutrient for human health. Front Physiol. 2014 Jul 11;5:248. doi: 10.3389/fphys.2014.00248. PMID: 25071593; PMCID: PMC4092358. https://pmc.ncbi.nlm.nih.gov/articles/PMC4092358/

Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol. 2014 Mar 20;21(3):319-29. doi: 10.1016/j.chembiol.2013.12.016. Epub 2014 Feb 13. PMID: 24529992; PMCID: PMC3968073. https://pmc.ncbi.nlm.nih.gov/articles/PMC3968073/

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