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Copper GHK Anti-Aging Serum

 

“Total Restoration Formula”

 

GHK is a copper peptide that was discovered in 1973 by the late Dr. Loren Pickart PhD. GHK occurs naturally in human blood. GHK levels appear to be higher in younger people than older people. Out of that finding, it was determined that to improve skin appearance following laser resurfacing and chemical peels, adding more copper peptides to the surface of the skin could generate amazing results.

 

GHK Studies

 

The human copper-binding peptide GHK-Cu (glycyl-l-histidyl-l-lysine) is a small, naturally occurring tri-peptide present in human plasma that also can be released from tissues in case of an injury. Since its discovery in 1973, GHK-Cu established itself as a powerful protective and regenerative ingredient, which is currently widely used in skin and hair products

 

Up-to-date, it is established that GHK-Cu is able to:

 

    • Tighten loose skin and reverse thinning of aged skin
    • Repair protective skin barrier proteins
    • Improve skin firmness, elasticity, and clarity
    • Reduce fine lines, depth of wrinkles, and improve structure of aged skin
    • Smooth rough skin
    • Reduce photodamage, mottled hyperpigmentation, skin spots and lesions
    • Improve overall skin appearance
    • Stimulate wound healing
    • Protect skin cells from UV radiation
    • Reduce inflammation and free radical damage
    • Increase hair growth and thickness, enlarge hair follicle size [0].

 

Facial studies

 

Copper peptide GHK-Cu is widely used in anti-aging cosmetics (INCI name: Copper tripeptide-1).  Several controlled facial studies confirmed anti-aging, firming and anti-wrinkle activity of copper peptide GHK-Cu.

 

Facial cream containing GHK-Cu and melatonin increased collagen in photoa-ged skin of 20 female volunteers, performing better than vitamin C and retinoic acid. The study was not controlled for cream vehicle application alone without active ingredients.

 

A 12-week facial study on 67 women indicated that GHK-Cu cream applied twice daily improved aged skin appearance, increased thickness, reduced wrinkles and strongly stimulated dermal keratinocyte proliferation as determined by histological analysis of biopsies. The same study found copper peptide GHK-Cu to be non-toxic and non-irritating.

 

Hair growth

 

Copper peptide GHK-Cu and its analogues were found to stimulate hair growth. In some circumstances, the efficiency of synthetic analog of GHK-Cu was similar to that of 5% minoxidil. A commercial product GraftCyte was clinically proven to improve hair transplantation outcome. Shown to promote collagen production, using copper peptides topically on the scalp will help strengthen already existing hair, while stimulating growth in areas that are lacking thickness.

 

Anti-inflammatory activity

 

GHK peptide has anti-inflammatory properties but the mechanism remains unclear. GHK and its copper complexes decreased TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts. Because of the anti-inflammatory properties, copper-peptides could replace corticosteroids or non-steroidal anti-inflammatory drugs in treatment of inflammatory skin conditions. They also can reduce UV-induced Erythema.

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